Medication Persistence Rates and Factors Associated with Persistence in Patients Following Stroke: A Cohort Study
2008

Medication Persistence in Stroke Patients

Sample size: 420 publication 10 minutes Evidence: high

Author Information

Author(s): Lummis Heather L, Sketris Ingrid S, Gubitz Gordon J, Joffres Michel R, Flowerdew Gordon J

Primary Institution: Queen Elizabeth II Health Sciences Centre

Hypothesis

How well do stroke patients continue taking their prescribed medications over time?

Conclusion

Patients reported high medication persistence rates six and 12 months after stroke.

Supporting Evidence

  • 96% of patients were prescribed an antithrombotic at discharge.
  • Medication persistence was high, exceeding 90% at six and twelve months.
  • Older age and prior disability were associated with nonpersistence.

Takeaway

After having a stroke, most patients keep taking their medicines for a long time, which helps them stay healthy.

Methodology

Patients admitted with stroke were followed for one year, and their medication use was tracked at discharge, six months, and twelve months.

Potential Biases

Self-reporting could lead to misclassification of medication adherence.

Limitations

Reasons for non-persistence were not formally documented, and self-reported medication use may not be accurate.

Participant Demographics

Mean age was 68.2 years, with 55.7% male.

Statistical Information

P-Value

0.0003

Confidence Interval

0.03–0.39

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2377-8-25

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication