Acute Sarcopenia: Review of Its Incidence and Muscle Changes During Hospitalization
Author Information
Author(s): Aldrich Luke, Ispoglou Theocharis, Prokopidis Konstantinos, Alqallaf Jasem, Wilson Oliver, Stavropoulos‐Kalinoglou Antonis
Primary Institution: Leeds Beckett University
Hypothesis
What is the incidence of acute sarcopenia and how do muscle parameters change during hospitalization?
Conclusion
Acute sarcopenia is underdiagnosed during hospitalization, with an incidence of 18% and varying effects on muscle parameters.
Supporting Evidence
- 18% of hospitalized patients developed acute sarcopenia during their stay.
- Muscle mass and quality indices are more affected than upper limb strength or overall muscle function.
- Handgrip strength remained stable despite significant reductions in muscle mass.
- Muscle function tests may not be sensitive enough to detect acute changes during hospitalization.
Takeaway
When people go to the hospital, their muscles can get weaker really fast, and many don't even know it. This can make it harder for them to get better.
Methodology
The review included 88 studies, with meta-analyses on handgrip strength, rectus femoris cross-sectional area, and muscle function tests.
Potential Biases
Variability in patient demographics and hospital exposures may introduce bias in the findings.
Limitations
High heterogeneity among studies and variability in assessment methods limited the ability to draw clear conclusions.
Participant Demographics
Patients ranged from 33 to 88 years old, with a mix of medical and surgical conditions.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI = −0.92:−0.43
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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