Radiotherapy for Squamous Cell Carcinoma in Chronic Lymphocytic Leukemia Patients
Author Information
Author(s): Wong J., Breen D., Balogh J., Czarnota G.J., Kamra J., Barnes E.A.
Primary Institution: University of Toronto, Faculty of Medicine, Odette Cancer Centre, Sunnybrook Health Sciences Centre
Hypothesis
Can radiotherapy effectively manage locally aggressive cutaneous squamous cell carcinoma in patients with chronic lymphocytic leukemia?
Conclusion
Radiotherapy can provide local control for cutaneous squamous cell carcinoma in patients with chronic lymphocytic leukemia, although local recurrence is common.
Supporting Evidence
- All patients had locally aggressive cutaneous squamous cell carcinoma managed with radiotherapy after local recurrence.
- Two patients achieved complete regression of disease, while two had local recurrence after treatment.
- Radiotherapy was delivered with curative intent for all patients.
Takeaway
This study looked at 4 patients with a type of blood cancer who got skin cancer. They were treated with radiation, which helped shrink the tumors, but some grew back later.
Methodology
The study involved 4 patients with chronic lymphocytic leukemia who were treated with radiotherapy after local recurrence of cutaneous squamous cell carcinoma following surgical excision.
Limitations
The study is limited by the small sample size and the lack of long-term follow-up for all patients.
Participant Demographics
All patients were elderly, with a mean age of 84 years, and had a history of chronic lymphocytic leukemia.
Want to read the original?
Access the complete publication on the publisher's website