Neuronal plasticity in a case with total hemispheric lesion
2011
Neuronal Plasticity in a Case with Total Hemispheric Lesion
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Ipek M, Hilal H, Nese T, Aynur M, Gazanfer E
Primary Institution: Marmara University Hospital
Hypothesis
Can the adult brain reorganize and recover function after total left hemisphere damage?
Conclusion
A patient with a complete left hemisphere lesion can still speak and live independently due to neuronal reorganization.
Supporting Evidence
- The patient had a total left hemisphere encephalomalasia but could still speak and perform daily activities.
- Functional MRI showed right hemisphere activation during voluntary movement of the right leg.
- Despite the extensive damage, the patient exhibited only mild cognitive dysfunction.
Takeaway
Even if one side of the brain is damaged, the other side can help a person still talk and do things on their own.
Methodology
Case report detailing the patient's neurological examination, MRI, and functional MRI results.
Limitations
The study is based on a single case, limiting generalizability.
Participant Demographics
25-year-old female patient.
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