Beneficial Effects of a Nutraceutical Combination on Lipid Profiles in Children with Moderate and Severe Hypercholesterolemia
2024

Effects of a Nutraceutical on Cholesterol in Children

Sample size: 84 publication 10 minutes Evidence: moderate

Author Information

Author(s): Garoufi Anastasia, Papadaki Maria, Kalogiannis Michalis, Zerva Urania, Charakida Marietta, Marmarinos Antonios, Attilakos Achilleas

Primary Institution: National and Kapodistrian University of Athens

Hypothesis

The study aims to evaluate the efficacy and safety of a dietary supplement containing red yeast rice and other natural compounds in children with primary hypercholesterolemia.

Conclusion

The nutraceutical Armolipid significantly reduced cholesterol levels in children with moderate and severe hypercholesterolemia without adverse effects.

Supporting Evidence

  • Nutraceutical consumption resulted in a significant decrease in total cholesterol and LDL cholesterol levels.
  • 84 children were evaluated, with 64 having a second evaluation after treatment.
  • More than 60% of participants showed a decrease in atherogenic lipoproteins.
  • No adverse effects were reported during the study.
  • Armolipid may be an effective complementary treatment for children with hypercholesterolemia.

Takeaway

Kids with high cholesterol can take a special supplement that helps lower their cholesterol levels safely.

Methodology

A prospective single-center cohort study was conducted with clinical and laboratory evaluations before and after treatment with the nutraceutical.

Potential Biases

Potential bias due to reliance on self-reported compliance with supplement intake.

Limitations

The study lacked a control group and had a relatively small sample size, which may affect the generalizability of the findings.

Participant Demographics

84 children and adolescents aged 7 to 16 years, with a near-equal gender distribution.

Statistical Information

P-Value

p < 0.001

Statistical Significance

p < 0.001

Digital Object Identifier (DOI)

10.3390/biom14121608

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