Effect of home-based transcranial direct current stimulation (tDCS) on cognitive functioning in bipolar depression
2024

Home-based tDCS for Cognitive Functioning in Bipolar Depression

Sample size: 44 publication Evidence: moderate

Author Information

Author(s): Rezaei Hakimeh, Woodham Rachel D., Ghazi-Noori Ali-Reza, Ritter Philipp, Bramon Elvira, Bauer Michael, Young Allan H., Fu Cynthia H.Y.

Hypothesis

The study aimed to assess the cognitive effects of home-based transcranial direct current stimulation (tDCS) in individuals with bipolar depression.

Conclusion

Cognitive performance improved in individuals with bipolar depression after treatment with home-based tDCS.

Supporting Evidence

  • 93.18% of participants completed the Rey Auditory Verbal Learning Test (RAVLT).
  • 59.09% of participants completed the Symbol Digit Modalities Test (SDMT).
  • Significant improvement was observed in the RAVLT short-term verbal memory score post-treatment.

Takeaway

This study tested a new way to help people with bipolar depression think better using a special device at home.

Methodology

Participants received 21 sessions of home-based tDCS over 6 weeks, with cognitive assessments conducted at baseline and after treatment.

Participant Demographics

44 participants (31 women, mean age 47.27 ± 12.89 years) experiencing moderate to severe depressive episodes.

Statistical Information

P-Value

0.002

Statistical Significance

p = 0.002

Digital Object Identifier (DOI)

10.21203/rs.3.rs-5396838

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