Ginsenosides, salidroside, and syringin complex exhibits anti-fatigue in exhaustive exercise rats
2025

Chinese Herb Powder Reduces Fatigue in Rats

Sample size: 32 publication 10 minutes Evidence: moderate

Author Information

Author(s): Wu Yung-Chun, Lian Yu Zhi, Zhao Hongwei, Wang Lei, Ning Deshan, Chao Jane C.-J.

Primary Institution: Taipei Medical University

Hypothesis

The study investigates whether a mixture of ginsenosides, salidroside, and syringin can improve exercise performance and reduce fatigue in rats.

Conclusion

High-dose Chinese herb powder significantly increased the time to exhaustion and improved lactate clearance in rats, indicating its anti-fatigue effects.

Supporting Evidence

  • The high-dose group showed a significant increase in time to exhaustion compared to the control group.
  • Serum lactate levels decreased significantly after 30 minutes of rest in the intervention groups.
  • High-dose CHP increased serum superoxide dismutase activity.
  • Liver interleukin-6 levels were significantly reduced in the medium- and high-dose groups.

Takeaway

Giving rats a special mix of herbs helped them run longer without getting tired.

Methodology

Male Sprague-Dawley rats were divided into four groups and given different doses of Chinese herb powder for 30 days, followed by exercise tests to measure performance and biochemical markers.

Potential Biases

Potential bias due to authors' affiliations with the company providing the herb powder.

Limitations

The study was conducted on rats, and results may not directly translate to humans.

Participant Demographics

32 male Sprague-Dawley rats, aged 8 weeks.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.7150/ijms.99889

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