The role of antioxidant supplement in immune system, neoplastic, and neurodegenerative disorders: a point of view for an assessment of the risk/benefit profile
2008

The Role of Antioxidant Supplements in Health

publication Evidence: moderate

Author Information

Author(s): Brambilla Daria, Mancuso Cesare, Scuderi Mariagrazia Rita, Bosco Paolo, Cantarella Giuseppina, Lempereur Laurence, Di Benedetto Giulia, Pezzino Salvatore, Bernardini Renato

Primary Institution: University of Catania

Hypothesis

What is the risk/benefit profile of dietary antioxidants in chronic diseases?

Conclusion

Antioxidants may provide some benefits, but their excessive use can lead to health risks.

Supporting Evidence

  • Reactive oxygen species are linked to many diseases.
  • Antioxidants can protect cells but may also cause harm if taken excessively.
  • Certain vitamins have been associated with increased cancer risk.

Takeaway

Antioxidants can help keep our bodies healthy, but too much can actually make us sick.

Potential Biases

Potential bias due to the review nature and lack of original data.

Limitations

The review discusses the potential risks of antioxidants but does not provide specific clinical trial data.

Digital Object Identifier (DOI)

10.1186/1475-2891-7-29

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