Inverse planned stereotactic intensity modulated radiotherapy (IMRT) in the treatment of incompletely and completely resected adenoid cystic carcinomas of the head and neck: initial clinical results and toxicity of treatment
2006

Using IMRT to Treat Adenoid Cystic Carcinomas in the Head and Neck

Sample size: 25 publication Evidence: moderate

Author Information

Author(s): Münter MW, Schulz-Ertner D, Hof H, Nikoghosyan A, Jensen A, Nill S, Huber P, Debus J

Primary Institution: German Cancer Research Center (dkfz), Heidelberg, Germany

Hypothesis

Is inverse planned stereotactic intensity modulated radiotherapy (IMRT) effective in treating adenoid cystic carcinomas of the head and neck?

Conclusion

The inverse planned stereotactic IMRT is feasible in the treatment of ACC, achieving high control rates and low side effects.

Supporting Evidence

  • The three-year overall survival rate was 72%.
  • The three-year recurrence-free survival was 38%.
  • Acute side effects >Grade II appeared in a small number of patients.

Takeaway

Doctors used a special type of radiation therapy to treat patients with a specific kind of cancer in the head and neck, and it worked well with few side effects.

Methodology

25 patients with adenoid cystic carcinomas were treated using inverse planned IMRT, with follow-up evaluations conducted over a median of 22.5 months.

Limitations

The study had a small sample size and a relatively short follow-up period.

Participant Demographics

Patients aged 30 to 80 years, with 12 females and 13 males.

Digital Object Identifier (DOI)

10.1186/1748-717X-1-17

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