Analysis of the insertion/deletion polymorphism of the human angiotensin converting enzyme (ACE) gene in patients with renal cancer
2000
Study of ACE Gene Variations in Renal Cancer Patients
Sample size: 58
publication
Author Information
Author(s): Usmani B A, Janeczko M, Shen R, Mazumdar M, Papandreou C N, Nanus D M
Primary Institution: Memorial Sloan-Kettering Cancer Center
Hypothesis
Is there a significant difference in the distribution of ACE gene polymorphisms between renal cancer patients and the normal population?
Conclusion
The distribution of ACE gene polymorphisms in renal cancer patients is similar to that of the normal population.
Supporting Evidence
- The study analyzed the ACE gene polymorphism in renal cancer patients.
- The frequencies of the D and I alleles were determined.
- No significant difference was found between cancer patients and the normal population.
Takeaway
The study looked at a gene that might be linked to kidney cancer, but found that people with kidney cancer have similar gene variations as those without it.
Methodology
DNA was extracted from kidney tissues of renal cancer patients to determine the frequencies of ACE gene polymorphisms.
Participant Demographics
Renal cancer patients
Digital Object Identifier (DOI)
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