A polymorphism in the CYP17 gene is associated with male breast cancer
1999

CYP17 Gene and Male Breast Cancer Risk

publication

Author Information

Author(s): Young I E, Kurian K M, Annink C, Kunkler I H, Anderson V A, Cohen B B, Hooper M L, Wyllie A H, Steel C M

Primary Institution: University of Edinburgh

Hypothesis

Is there an association between a polymorphism in the CYP17 gene and male breast cancer risk?

Conclusion

The study found that a polymorphism in the CYP17 gene is linked to a higher risk of male breast cancer.

Supporting Evidence

  • The CYP17 gene is involved in estrogen synthesis.
  • The study indicates a genetic risk factor for male breast cancer.

Takeaway

This study suggests that a specific change in a gene can make men more likely to get breast cancer.

Methodology

This is a case-control study conducted in South East Scotland.

Digital Object Identifier (DOI)

10.1038/sj.bjc.6690663

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