Cost-effectiveness of Rotavirus Vaccine in Mexico
Author Information
Author(s): Atanacio Valencia-Mendoza, Stefano M Bertozzi, Juan-Pablo Gutierrez, Robbin Itzler
Primary Institution: National Institute of Public Health, Mexico
Hypothesis
The study aims to assess the cost-effectiveness of including the pentavalent rotavirus vaccine in Mexico's national immunisation program.
Conclusion
The rotavirus vaccine is highly cost-effective in Mexico, especially at prices below $15 per dose.
Supporting Evidence
- Vaccination could prevent 71,464 medical visits, 5,040 hospital admissions, and 612 deaths.
- The cost per death prevented is estimated at $122,058.
- The cost per discounted life-year saved is $4,283.
- At prices below $15 per dose, the vaccine is highly cost-effective.
Takeaway
Vaccinating children against rotavirus can save many lives and reduce hospital visits, making it a smart choice for health programs.
Methodology
A cost-effectiveness model was developed comparing vaccinated and unvaccinated cohorts of children.
Potential Biases
The model may underestimate the true cost-effectiveness of the vaccine due to simplifications.
Limitations
The model does not account for potential vaccine side effects or the impact of illness on parental productivity.
Participant Demographics
The study focuses on a hypothetical birth cohort of 2 million children in Mexico.
Statistical Information
Confidence Interval
95% CI for efficacy against severe gastroenteritis is 88.3 to 100%.
Digital Object Identifier (DOI)
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