Long-term effects on sexual function and fertility after treatment of testicular cancer
1999

Long-term effects on sexual function and fertility after testicular cancer treatment

Sample size: 98 publication Evidence: moderate

Author Information

Author(s): Hartmann J T, Albrecht C, Schmoll H-J, Kuczyk M A, Kollmannsberger C, Bokemeyer C

Primary Institution: Hanover University Medical School

Hypothesis

Does the type of treatment for testicular cancer affect sexual function and fertility in survivors?

Conclusion

Sexual dysfunction and infertility are common long-lasting effects in testicular cancer survivors, impacting about 20% of patients.

Supporting Evidence

  • Ninety-eight patients were included in the study, representing a response rate of 78%.
  • Twenty patients (20%) had been treated for seminomatous and 78 patients (80%) for non-seminomatous germ cell tumours.
  • Patients receiving two treatment modalities reported more frequent unfulfilled wishes for children.
  • Inability of ejaculation was clearly associated with certain treatment modalities.
  • No congenital abnormalities were observed in the children of patients who fulfilled their wish for children.

Takeaway

This study found that many men who survived testicular cancer have problems with sex and having kids, especially if they had certain treatments.

Methodology

A retrospective study using a self-reported questionnaire sent to 124 patients treated at Hanover University Medical School.

Potential Biases

Potential bias due to self-reporting and the retrospective nature of the study.

Limitations

The study relies on self-reported data, which may introduce bias.

Participant Demographics

Median age at diagnosis was 28 years, with a range of 17 to 44 years.

Digital Object Identifier (DOI)

10.1038/sj.bjc.6690424

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