Frequencies of Maternal Red Blood Cell Alloantibodies in Port Harcourt, Nigeria
Author Information
Author(s): Jeremiah Zaccheaus A. Mordi, Buseri Fiekumo I. Adias, Teddy C.
Primary Institution: Braithwaite Memorial Specialist Hospital, Port Harcourt, Nigeria
Hypothesis
To determine the frequency of occurrence of alloantibodies among pregnant women in Port Harcourt, Nigeria.
Conclusion
The study identified a 3.4% prevalence of non-Rh D antibodies among pregnant women, with no anti-D antibodies found.
Supporting Evidence
- 3.4% of the pregnant women had alloantibodies.
- Anti-C was the most frequent antibody detected at 1.2%.
- No anti-D antibodies were found despite a significant percentage of Rh D negative women.
Takeaway
The study found that a small number of pregnant women have certain antibodies that could affect their babies, but none had a specific antibody that is usually a concern.
Methodology
A prospective study was conducted where 500 pregnant women were screened for red blood cell alloantibodies using specific reagents.
Limitations
The study was limited to a single hospital and may not represent the entire population of pregnant women in the region.
Participant Demographics
The majority of participants were aged 26-30 years, in their second trimester, and mostly multiparous.
Statistical Information
P-Value
0.670
Statistical Significance
p=0.670
Digital Object Identifier (DOI)
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