Efficacy of Genicular Nerve Block in Patients with Osteoarthritis: A Comparative Study with and without Fluoroscopy Assistance
2024

Efficacy of Genicular Nerve Block in Patients with Osteoarthritis

Sample size: 23 publication Evidence: moderate

Author Information

Author(s): Said Nour Aliman El Majzoub, Mestriner Alexandre Barbieri, Sungaila Heloisa, Mameri Enzo Salviato, Franciozi Carlos Eduardo Silveira, Kubota Marcelo Seiji

Primary Institution: Escola Paulista de Medicina, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, Brasil

Hypothesis

Does fluoroscopy improve the efficacy of genicular nerve block compared to anatomical guidance alone in reducing pain in osteoarthritis patients?

Conclusion

Both fluoroscopy-guided and anatomical parameter-based genicular nerve blocks were equally effective in reducing pain.

Supporting Evidence

  • The WOMAC pain subscale showed significant pain reduction in both groups at all time points.
  • Pain reduction was greater after 1 hour in both groups, with no significant difference.
  • The VAS also showed significant pain reduction in both groups at all times.
  • At the end of 90 days, pain reduction rates were 35.7% in the fluoroscopy group and 44.6% in the anatomical parameter group.

Takeaway

This study looked at two ways to help people with knee pain from arthritis feel better. Both ways worked just as well!

Methodology

A quasi-randomized clinical trial comparing fluoroscopy-guided and anatomical parameter-based genicular nerve blocks in 23 patients, measuring pain at multiple time points using WOMAC and VAS.

Limitations

The study did not reach the minimum sample size of 56 patients and did not perform multivariate analysis for comorbidities.

Participant Demographics

Mean age 64.5 years, 69.6% female, mean BMI 31.4 kg/m².

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1055/s-00042410

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