Somatostatin for Bleeding Oesophagitis or Ulceration After Sclerotherapy
Author Information
Author(s): S.A. Jenkins, R. Shields, N. Jaser, S. Ellenbogen, C. Makin, E. Naylor, M. Newstead, J.N. Baxter
Hypothesis
Is somatostatin effective in controlling bleeding from oesophagitis or ulcers after sclerotherapy for oesophageal varices?
Conclusion
Somatostatin is an effective and safe treatment for controlling bleeding from oesophagitis or ulcers following injection sclerotherapy of oesophageal varices.
Supporting Evidence
- Somatostatin was effective in controlling haemorrhage in all patients with oesophagitis and most with ulcers.
- Two patients required additional bolus injections for persistent bleeding.
- The study suggests somatostatin is a viable treatment option for managing bleeding complications after sclerotherapy.
Takeaway
This study shows that somatostatin can help stop bleeding in patients who have had problems after treatment for varices in the esophagus.
Methodology
Twenty-two patients were treated with intravenous somatostatin after experiencing severe haemorrhage from oesophagitis or ulcers following sclerotherapy.
Limitations
The study does not compare somatostatin's effectiveness with other treatments in a controlled trial.
Participant Demographics
Patients with severe haemorrhage from oesophagitis or ulcers after sclerotherapy.
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