Mapping Candidate Sex-Determining Genes in Rainbow Trout
Author Information
Author(s): Alfaqih Mahmoud A, Brunelli Joseph P, Drew Robert E, Thorgaard Gary H
Primary Institution: Washington State University
Hypothesis
In a tetraploid-derived organism like the rainbow trout, any gene in the sex differentiation cascade, or its homologue, could potentially have evolved as a sex-determining gene.
Conclusion
Additional candidate genes should be tested for their linkage to the Y chromosome.
Supporting Evidence
- Five loci of four candidate genes were tested for linkage to the Y chromosome of rainbow trout.
- All tested loci were excluded as candidates for the primary sex-determining gene.
- Sox6i and Sox6ii were identified as duplicated copies of Sox6.
Takeaway
Scientists looked for genes that might determine the sex of rainbow trout and found that the ones they tested didn't work as the main sex-determining gene.
Methodology
Linkage analysis was performed on candidate genes to test their association with the Y chromosome in rainbow trout.
Limitations
The study did not find the primary sex-determining gene and focused only on a limited number of candidate genes.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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