Invasive Bacterial Diseases in Northern Canada
Author Information
Author(s): Degani Naushaba, Navarro Christine, Deeks Shelley L., Lovgren Marguerite
Primary Institution: Hospital for Sick Children, Toronto, Ontario, Canada
Hypothesis
How do invasive bacterial diseases affect northern populations in Canada?
Conclusion
The study found that invasive bacterial diseases, particularly caused by Streptococcus pneumoniae, remain a significant health issue in northern Canada, especially among aboriginal populations.
Supporting Evidence
- Crude annual incidence rates of invasive Streptococcus pneumoniae decreased from 34.0/100,000 population (1999–2002) to 23.6/100,000 population (2003–2005).
- Aboriginal populations had higher incidence rates of S. pneumoniae, Haemophilus influenzae, and group A streptococci compared to non-aboriginal populations.
- Implementation of universal PCV7 programs was associated with a reduction in PCV7-preventable illness in children under 2 years of age.
Takeaway
This study looked at how serious bacterial infections affect people living in the northern parts of Canada, especially kids and older adults. It found that these infections are more common in aboriginal people.
Methodology
Data were collected through a population-based surveillance network, with cases defined as persons from whom an organism under surveillance is isolated from normally sterile sites.
Potential Biases
Potential biases include underreporting of cases and lack of complete vaccination coverage data.
Limitations
The number of reported cases is too small for detailed analysis, and the data may underestimate the true incidence of invasive bacterial diseases.
Participant Demographics
The study included a population of 132,956, with 59% identifying as aboriginal.
Statistical Information
P-Value
0.119
Statistical Significance
p = 0.119
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website