3,5-Bis(4-chlorobenzylidene)-1-methylpiperidin-4-one
2011
Crystal Structure of 3,5-Bis(4-chlorobenzylidene)-1-methylpiperidin-4-one
publication
Evidence: moderate
Author Information
Author(s): Volodymyr V. Nesterov, Sergey S. Sarkisov, Vladimir Shulaev, Vladimir N. Nesterov
Primary Institution: New Mexico Highlands University
Hypothesis
The study investigates the crystal structure of a compound with potential anticancer properties.
Conclusion
The compound exhibits a flattened boat conformation and forms weak hydrogen bonds in the crystal structure.
Supporting Evidence
- The compound may help locate cancer cells using two-photon excited fluorescence.
- It has shown anticancer activity in previous studies.
- The molecular structure includes weak intermolecular hydrogen bonds.
Takeaway
Scientists looked at how a specific chemical compound is arranged in a crystal, which might help in cancer treatment.
Methodology
The compound was synthesized and characterized using NMR spectroscopy and X-ray crystallography.
Digital Object Identifier (DOI)
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