Meningoencephalomyelitis and brachial plexitis in a dog infected with louping ill virus
2024

Meningoencephalomyelitis and Brachial Plexitis in a Dog Infected with Louping Ill Virus

Sample size: 1 publication Evidence: low

Author Information

Author(s): Sai Fingerhood, Mansfield Karen L., Folly Arran J., Gomez Vitores Ana, Rocchi Mara, Clarke Dominic, Gola Cecilia

Primary Institution: University of Surrey Veterinary Pathology Centre

Hypothesis

Canine louping ill virus infection can cause meningoencephalomyelitis and brachial plexitis.

Conclusion

This study provides the first characterization of louping ill virus-related inflammatory lesions in a dog, highlighting its potential as a differential diagnosis for similar neurological conditions.

Supporting Evidence

  • The dog exhibited severe neurologic signs including tremors and seizures.
  • Histological examination revealed severe meningoencephalomyelitis and mild brachial plexitis.
  • Louping ill virus was detected in the brain tissue of the dog.
  • This is the first report of louping ill virus affecting the spinal cord and brachial plexus in a dog.

Takeaway

A dog got very sick and had to be put to sleep because it had a virus that caused brain and nerve problems. This virus is usually found in sheep and ticks.

Methodology

The dog underwent postmortem examination, histopathology, and molecular analysis to identify the louping ill virus.

Limitations

The study is based on a single case, limiting the generalizability of the findings.

Participant Demographics

A 3-year-old intact female foxhound from south Devon, UK.

Digital Object Identifier (DOI)

10.1177/03009858241265035

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