Dragon Database for Exploration of Sodium Channels in Humans
Author Information
Author(s): Sagar Sunil, Kaur Mandeep, Dawe Adam, Seshadri Sundararajan Vijayaraghavan, Christoffels Alan, Schaefer Ulf, Radovanovic Aleksandar, Bajic Vladimir B
Primary Institution: South African National Bioinformatics Institute, University of the Western Cape
Hypothesis
There is a need for a comprehensive public resource that allows users to explore information related to sodium channels from multiple angles.
Conclusion
DDESC is the first publicly available resource where the information related to sodium channels in humans can be explored at different levels.
Supporting Evidence
- DDESC provides comprehensive information about sodium channels, including genes, proteins, metabolites, and disease concepts.
- The database allows users to explore potential associations between different entities related to sodium channels.
- DDESC is freely accessible for academic and non-profit users via the worldwide web.
- The database is regularly updated to include new studies.
- Text-mining techniques were used to compile the database from a large number of abstracts.
Takeaway
The DDESC is a new online database that helps scientists find information about sodium channels, which are important for understanding certain diseases.
Methodology
The database was compiled using text- and data-mining techniques from 5,243 abstracts retrieved from PubMed.
Potential Biases
The dictionary-based method may lead to misidentification of entities due to synonyms and abbreviations.
Limitations
The accuracy of the database may vary for different entities, and some entities may be misidentified due to naming conventions.
Digital Object Identifier (DOI)
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