Antimicrobial and antioxidant properties of methanol extract, fractions and compounds from the stem bark of Entada abyssinica
2011

Antimicrobial and Antioxidant Properties of Entada abyssinica

publication Evidence: moderate

Author Information

Author(s): Teke Gerald N, Lunga Paul K, Wabo Hippolyte K, Kuiate Jules-Roger, Vilarem Gerard, Giacinti Geraldine, Kikuchi Haruhisa, Oshima Yoshiteru

Primary Institution: University of Dschang, Cameroon

Hypothesis

The study aims to evaluate the antimicrobial and antioxidant activities of the methanol extract, fractions, and isolated compounds from Entada abyssinica stem bark.

Conclusion

The study supports the traditional use of E. abyssinica for treating gastrointestinal infections and suggests that its isolated compounds may be useful in developing antimicrobial phytomedicine.

Supporting Evidence

  • The methanol extract and fractions showed significant antimicrobial activity against various bacteria and yeasts.
  • Isolated compounds demonstrated varying degrees of antibacterial and antifungal activities.
  • The antioxidant activity was assessed using the DPPH radical scavenging method, with some compounds showing strong activity.

Takeaway

This study found that a plant called Entada abyssinica can help fight germs and might be good for making medicine.

Methodology

The study involved extracting the stem bark with methanol, fractionating it, and testing the antimicrobial and antioxidant activities using various assays.

Statistical Information

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1472-6882-11-57

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