Clinical Profile of Acute Disseminated Encephalomyelitis in Children
Author Information
Author(s): Jayakrishnan M.P., Krishnakumar P.
Primary Institution: Institute of Maternal and Child Health, Medical College, Calicut, Kerala, India
Hypothesis
To study the clinical profile of acute disseminated encephalomyelitis (ADEM) in children.
Conclusion
Despite the serious neuropsychiatric manifestations, ADEM in children generally has good immediate outcomes.
Supporting Evidence
- Acute febrile illness preceded the onset of neurological symptoms in 64% of children.
- All children recovered fully, although some had residual symptoms.
- 50% of children assessed had borderline IQ.
Takeaway
This study looked at how a brain condition called ADEM affects kids, and most of them got better after treatment.
Methodology
Children admitted with ADEM were treated with intravenous methyl prednisolone and followed up for varying periods.
Limitations
The study did not assess the presence of oligoclonal bands in CSF due to lack of facilities.
Participant Demographics
The sample consisted of 11 girls (79%) and 3 boys (21%), with ages ranging from 6 months to 12 years.
Digital Object Identifier (DOI)
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