Hepatitis B virus in Pakistan: A systematic review of prevalence, risk factors, awareness status and genotypes
2011

Hepatitis B Virus Prevalence in Pakistan

Sample size: 106 publication Evidence: moderate

Author Information

Author(s): Ali Muhammad, Idrees Muhammad, Ali Liaqat, Hussain Abrar, Ur Rehman Irshad, Saleem Sana, Afzal Samia, Butt Sadia

Primary Institution: Division of Molecular Virology, National Centre of Excellence in Molecular Biology, University of the Punjab

Hypothesis

What is the prevalence, risk factors, awareness status, and genotypes of Hepatitis B virus in Pakistan?

Conclusion

The study found that the prevalence of Hepatitis B virus infection varies significantly across different population groups in Pakistan, with some areas showing rates above 5%.

Supporting Evidence

  • An estimated 7-9 million people in Pakistan are carriers of Hepatitis B virus.
  • The overall prevalence of HBV infection in the general population was found to be 4.3318%.
  • Genotype D is the most prevalent genotype in the Pakistani population at 63.71%.
  • Mass vaccination and awareness programs are urgently needed in areas with high HBV infection rates.

Takeaway

Many people in Pakistan have Hepatitis B, and some groups are more affected than others. We need to help them understand the disease and get vaccinated.

Methodology

The study reviewed 106 different studies published from 1998 to 2010, analyzing prevalence rates and risk factors for HBV in various population groups.

Limitations

The review is limited to studies published until 2010 and may not reflect the most current data.

Participant Demographics

The review included various population groups such as healthy individuals, blood donors, military recruits, healthcare workers, pregnant women, prisoners, and patients with liver diseases.

Statistical Information

Confidence Interval

4.3318% ± 1.644%

Digital Object Identifier (DOI)

10.1186/1743-422X-8-102

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