Body Composition and Therapeutic Hypothermia After Cardiac Arrest
Author Information
Author(s): Jimmink Joost J, Binnekade Jan M, Paulus Frederique, Mathus-Vliegen Elisebeth MH, Schultz Marcus J, Vroom Margreeth B
Primary Institution: Academic Medical Centre, University of Amsterdam
Hypothesis
The variation of the time needed to achieve the target temperature was caused, at least in part, by patient factors such as weight and fat percentage.
Conclusion
Body composition measures from single-frequency impedance and anthropometrics appear to be very concordant, but only TBF percentage showed a significant but clinically irrelevant influence on time needed to achieve target temperature with hypothermia.
Supporting Evidence
- The median time to reach target temperature after admission was 191 minutes.
- Intraclass correlation for total body fat measures was 0.94.
- Only TBF percentage was associated with time to reach target temperature.
Takeaway
This study looked at how a person's body fat affects how quickly they can be cooled down after a heart problem. It found that body fat doesn't really change how fast they cool down.
Methodology
A prospective observational study was conducted on patients treated with hypothermia after out-of-hospital cardiac arrest, collecting data on body composition and time to reach target temperature.
Limitations
The main limitation of this study is the small sample size and subsequent lack of power.
Participant Demographics
The study included 27 consecutive OHCA patients, with 78% being male and a mean age of 60 years.
Statistical Information
P-Value
0.03
Confidence Interval
95% CI 0.87 to 0.99
Statistical Significance
p=0.03
Digital Object Identifier (DOI)
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