Predicting Heart Changes After a Heart Attack Using MRI
Author Information
Author(s): Mandry Damien, Heydari Bobak, Abdullah Shuaib, Chung YiuCho, Rehwald Wolfgang, Coelho-Filho Otavio R, Mongeon François-Pierre, Harris Alanna S, van der Geest Rob J, Jerosch-Herold Michael, Kwong Raymond Y
Primary Institution: Brigham and Women's Hospital, Boston, MA, USA
Hypothesis
T2-extent at baseline and changes during follow-up are associated with dynamic changes of infarct heterogeneity during the convalescence phase of infarct healing.
Conclusion
T2 extent early after an MI is a predictor of shrinkage of infarct size and regression of the peri-infarct zone.
Supporting Evidence
- 98% of patients showed hyperintense T2 myocardium at baseline.
- T2 size was inversely correlated with LVEF.
- Manual-tracing was correlated well with the semi-automated method.
Takeaway
Doctors used special MRI scans to see how a heart changes after a heart attack, and they found that certain measurements can help predict healing.
Methodology
Fifty-one patients underwent 3T cardiac MRI at two time points after an acute MI, assessing T2-weighted imaging and LV function.
Limitations
The clinical significance of persistent hyperintense T2 areas after initial infarct healing remains unknown.
Participant Demographics
40 men and 11 women, average age not specified.
Statistical Information
P-Value
<0.01
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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