Antifungal Activity of Denture Soft Lining Material Modified by Silver Nanoparticles
Author Information
Author(s): Chladek Grzegorz, Mertas Anna, Barszczewska-Rybarek Izabela, Nalewajek Teresa, Żmudzki Jarosław, Król Wojciech, Łukaszczyk Jan
Primary Institution: Silesian University of Technology
Hypothesis
The modification of soft liner materials with silver nanoparticles (AgNPs) has the potential to decrease the risks associated with the colonisation of soft liners by pathogenic fungi.
Conclusion
The study found that silicone soft lining materials modified with silver nanoparticles showed antifungal efficacy ranging from 16.3% to 52.5% against Candida albicans.
Supporting Evidence
- The antifungal efficacy (AFE) of composite samples was found to be between 16.3% and 52.5%.
- Increasing the concentration of AgNPs generally led to higher antifungal efficacy.
- The study confirmed that silver nanoparticles have biocidal effectiveness in dental applications.
Takeaway
This study tested a new way to make denture materials that can fight off fungi, which can cause infections in people's mouths.
Methodology
The study involved modifying silicone soft liner materials with varying concentrations of silver nanoparticles and testing their antifungal efficacy against Candida albicans in vitro.
Limitations
The study suggests that further research is needed to confirm the safety and efficacy of the modified materials in vivo.
Digital Object Identifier (DOI)
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