Advances in synthetic approach to and antifungal activity of triazoles
Author Information
Author(s): Shalini Kumari, Kumar Nitin, Drabu Sushma, Sharma Pramod Kumar, Trauner Dirk
Primary Institution: Meerut Institute of Engineering & Technology, Meerut, U. P., India
Hypothesis
The development of new antifungal agents targeting specific fungal structures or functions is being actively pursued.
Conclusion
Triazoles have significantly improved our ability to treat various fungal infections, although mortality rates remain high.
Supporting Evidence
- Triazoles exhibit a broad spectrum of pharmacological activity such as antifungal, antibacterial, anti-inflammatory, and anticancer.
- Triazole derivatives are known to be effective against various fungal infections including candidiasis and aspergillosis.
- Rapid developments in molecular mycology have led to a concentrated search for more target antifungals.
Takeaway
Triazoles are special chemicals that help fight off fungal infections, making it easier for doctors to treat sick people.
Methodology
The article reviews various synthetic methods and pharmacological activities of triazole compounds.
Limitations
The review does not provide specific experimental data or sample sizes.
Digital Object Identifier (DOI)
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