Trimethoprim-Sulfamethoxazole-Induced Pancytopenia: A Case Report
2024

Case Report of Pancytopenia from Trimethoprim-Sulfamethoxazole

Sample size: 1 publication Evidence: low

Author Information

Author(s): Muacevic Alexander, Adler John R, Chahal Jaspreet, Junko Gretchen

Primary Institution: Department of Internal Medicine, Edward Via College of Osteopathic Medicine, Blacksburg, USA

Hypothesis

Can trimethoprim-sulfamethoxazole cause severe pancytopenia?

Conclusion

The patient's severe pancytopenia resolved after stopping trimethoprim-sulfamethoxazole and receiving treatment.

Supporting Evidence

  • The patient developed symptoms of pancytopenia after starting TMP/SMX.
  • Laboratory tests confirmed low levels of white blood cells, red blood cells, and platelets.
  • Discontinuation of TMP/SMX led to improvement in blood cell counts.

Takeaway

A patient took a medicine called Bactrim and got very sick with low blood cell counts, but he got better after stopping the medicine.

Methodology

The case report details the patient's symptoms, treatment, and laboratory findings before and after stopping the medication.

Limitations

The report is based on a single case, limiting generalizability.

Participant Demographics

An 80-year-old male.

Digital Object Identifier (DOI)

10.7759/cureus.75113

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