Combined Extract from Dioscorea bulbifera and Zingiber officinale Helps Lungs Affected by Air Pollution
Author Information
Author(s): Kim In Young, Lee Hyo Lim, Choi Hye Ji, Ju Yeong Hyeon, Heo Yu Mi, Na Hwa Rang, Lee Dong Yeol, Jeong Won Min, Heo Ho Jin, Yoshida Yasuhiro
Primary Institution: Gyeongsang National University
Hypothesis
Can a combined extract of Dioscorea bulbifera and Zingiber officinale protect against respiratory damage caused by PM2.5 exposure?
Conclusion
The combined extract significantly improves respiratory health by reducing oxidative stress and inflammation caused by PM2.5.
Supporting Evidence
- DBZO improved cell viability in lung cells exposed to PM2.5.
- DBZO reduced levels of reactive oxygen species in treated cells.
- DBZO modulated antioxidant markers in lung tissues of mice.
- Histopathological analysis showed reduced lung damage in DBZO-treated mice.
- DBZO decreased inflammatory cell counts in blood and serum IgE levels.
Takeaway
This study shows that a mix of two plants can help protect your lungs from pollution damage.
Methodology
The study involved in vitro tests on lung cells and in vivo tests on BALB/c mice exposed to PM2.5.
Potential Biases
Potential bias due to lack of external funding and reliance on specific plant extracts.
Limitations
The study was conducted on mice, and results may not directly translate to humans.
Participant Demographics
BALB/c mice, male, 6 weeks old.
Statistical Information
P-Value
0.031
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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