Normal Sweat Secretion Despite Impaired Growth Hormone-Insulin-Like Growth Factor-I Axis in Obese Subjects
2011

Normal Sweat Secretion in Obese Women Despite Hormonal Changes

Sample size: 32 publication 10 minutes Evidence: moderate

Author Information

Author(s): Michael Højby Rasmussen, Anders Juul, Katharina M. Main, Jannik Hilsted

Primary Institution: University of Copenhagen

Hypothesis

Does sweat secretion capacity change in obese subjects with impaired growth hormone secretion?

Conclusion

Obese women have normal sweat secretion rates despite reduced growth hormone release and impaired IGF-I levels.

Supporting Evidence

  • Obese subjects had similar sweat secretion rates compared to non-obese subjects.
  • Weight loss did not change sweat secretion rates in obese subjects.
  • GH release was significantly lower in obese women before weight loss.

Takeaway

Even though obese women have lower growth hormone levels, they still sweat normally, which is surprising.

Methodology

The study involved 16 obese women and 16 non-obese women, measuring sweat secretion rates before and after a weight loss program.

Limitations

Some participants dropped out of the study due to lack of motivation.

Participant Demographics

16 severely obese women with a mean age of 29.5 years and 16 age-matched non-obese women.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1155/2011/493840

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