Comparison of Postoperative Complications after Endoscopic Submucosal Dissection: Differences of Insufflations and Anesthesias
2011

Comparing Postoperative Complications in Endoscopic Surgery

Sample size: 50 publication Evidence: moderate

Author Information

Author(s): Mori Hirohito, Kobara Hideki, Muramatsu Akemi, Inoue Hideyuki, Kobayashi Mitsuyoshi, Nomura Takako, Hagiike Masanobu, Izuishi Kunihiko, Suzuki Yasuyuki, Gong Jian, Masaki Tsutomu

Primary Institution: Kagawa Medical University School of Medicine

Hypothesis

Does CO2 insufflation and general anesthesia reduce postoperative complications compared to air insufflation and IV anesthesia in endoscopic submucosal dissection?

Conclusion

ESD with CO2 insufflation and general anesthesia is safer than ESD with air insufflation and IV anesthesia.

Supporting Evidence

  • Postoperative enlarged feeling of the abdomen was significantly lower in the CO2/GA group.
  • No severe unrest was observed in the CO2/GA group compared to 16% in the Air/IV group.
  • The study included 50 patients undergoing ESD for early gastric cancer.

Takeaway

Using CO2 instead of air during stomach surgery helps patients feel better afterward and have fewer problems.

Methodology

50 patients were divided into two groups: one with air insufflation and IV anesthesia, and the other with CO2 insufflation and general anesthesia, to compare postoperative complications.

Potential Biases

Potential bias from the study being conducted by a single operator.

Limitations

The study was limited to a single endoscopist's practice and may not generalize to other settings.

Participant Demographics

43 males and 7 females, aged 65 to 88.

Statistical Information

P-Value

0.0416

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1155/2011/709237

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