Effects of Diet and Supplements on Women with Knee Osteoarthritis
Author Information
Author(s): Teresa Magrans-Courtney, Colin Wilborn, Christopher Rasmussen, Maria Ferreira, Lori Greenwood, Bill Campbell, Chad M Kerksick, Erica Nassar, Rui Li, Mike Iosia, Matt Cooke, Kristin Dugan, Darryn Willoughby, LuAnn Soliah, Richard B Kreider
Primary Institution: Texas A&M University
Hypothesis
Sedentary obese women with knee OA initiating an exercise and weight loss program may experience more beneficial changes in body composition, functional capacity, and/or markers of health following a higher protein diet compared to a higher carbohydrate diet with or without GCM supplementation.
Conclusion
Circuit style resistance-training and weight loss improved functional capacity in women with knee OA, with marginal benefits from diet type and GCM supplementation.
Supporting Evidence
- Participants in both groups experienced significant reductions in body mass, fat mass, and body fat.
- Perception of knee pain and stiffness decreased significantly.
- Functional aerobic capacity increased more in the higher protein and GCM groups.
- Improvements in quality of life measures were observed across both diet groups.
- Weight loss was associated with significant improvements in markers of health.
Takeaway
Women with knee pain can feel better and get stronger by exercising and losing weight, and eating more protein might help a little, but both high protein and high carbohydrate diets worked well.
Methodology
Randomized, double-blind, placebo-controlled trial with 30 sedentary women participating in a 14-week exercise and weight loss program while following either a higher protein or higher carbohydrate diet.
Potential Biases
Potential bias due to self-reported dietary intake and reliance on participant compliance.
Limitations
Small sample size and short duration may limit the generalizability of the findings.
Participant Demographics
Sedentary women aged 54 ± 9 years, with a BMI of 33.3 ± 5 kg/m2 and clinically diagnosed knee OA.
Statistical Information
P-Value
p < 0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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