The Outcome of Cholangitis After Percutaneous Biliary Drainage in Neoplastic Jaundice
1993

Cholangitis Outcomes After Biliary Drainage in Cancer Patients

Sample size: 29 publication Evidence: moderate

Author Information

Author(s): RICCARDO A. AUDISIO, CARLO MOROSI, FEDERICO BOZZETTI, GUIDO COZZI, MASSIMO BELLOMI, PAOLA PISANI, ALESSANDRA PESTALOZZA, LEANDRO GENNARI, ALDO SEVERINI

Primary Institution: Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano

Hypothesis

What factors affect the outcome of cholangitis after percutaneous biliary drainage in jaundiced cancer patients?

Conclusion

Percutaneous biliary drainage-related cholangitis has a good chance of cure and a low mortality rate.

Supporting Evidence

  • Four patients (14%) died of biliary sepsis a median of one month after PTBD.
  • 25 patients survived a median of 6 months after the procedure.
  • Cholangitis occurred a median of 9 days from PTBD.
  • 50% of recoveries occurred within 5 months from the onset of cholangitis.

Takeaway

Doctors studied 29 cancer patients who got sick after a procedure to drain bile. They found that most of them got better, and only a few died from the illness.

Methodology

The study analyzed clinical data of 29 patients who developed cholangitis after percutaneous biliary drainage.

Limitations

The study was retrospective and had a small sample size.

Participant Demographics

13 males and 16 females, median age 55 years.

Statistical Information

Statistical Significance

p<0.05

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