Height, Body Mass Index, and Prostate Cancer in Norwegian Men
Author Information
Author(s): Engeland A, Tretli S, Bjørge T
Primary Institution: Norwegian Institute of Public Health
Hypothesis
What is the relationship between height, body mass index (BMI), and the risk of prostate cancer?
Conclusion
The study found that both height and BMI are positively associated with the risk of prostate cancer, particularly in men aged 50-59.
Supporting Evidence
- 33,314 prostate cancer diagnoses were observed in the study.
- The mean age at diagnosis was 73 years.
- Men with a BMI below 35.0 kg/m2 had an increasing risk of prostate cancer with increasing BMI.
- The tallest men had a relative risk of 1.72 compared to the shortest men.
- Only histologically verified prostate cancer diagnoses were included in the study.
- Men measured at age 20-29 had a higher risk of prostate cancer as they aged.
- 7 men were lost to follow-up out of 951,466 eligible men.
- The study had a follow-up period averaging 21 years.
Takeaway
Tall men and those who are overweight or obese are more likely to get prostate cancer. This is especially true for men in their 50s.
Methodology
The study used a cohort of men whose height and weight were measured between 1963 and 1975, linking this data to cancer registry records for follow-up.
Potential Biases
The study may have biases related to the accuracy of self-reported height and weight and the completeness of cancer registration.
Limitations
The study's results may be influenced by the lack of specific hypotheses for stratified analyses and potential biases in cancer registration.
Participant Demographics
The cohort consisted of Norwegian men aged 20-74 years at the time of measurement.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI: 1.04–1.14
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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