Oral maxillofacial neoplasms in an East African population: a 10 year retrospective study of 1863 cases using histopathological reports
2008

Oral Maxillofacial Neoplasms in East Africa: A 10-Year Study

Sample size: 1863 publication Evidence: moderate

Author Information

Author(s): Kamulegeya Adriane, Kalyanyama Boniphace M

Primary Institution: Makerere University, Uganda; Muhimbili University of Health and Allied Sciences, Tanzania

Hypothesis

What are the histopathological diagnoses of oral maxillofacial neoplasms in East Africa over a 10-year period?

Conclusion

The study highlights a high prevalence of malignant neoplasms in oral maxillofacial cases in East Africa, necessitating a reexamination of histopathological classifications.

Supporting Evidence

  • 67.28% of the diagnoses recorded were malignant neoplasms.
  • Kaposi's sarcoma, Burkitt's lymphoma, and squamous cell carcinoma were the most common malignant neoplasms.
  • The study included 1863 cases of oral maxillofacial neoplasms.

Takeaway

Doctors looked at a lot of cases of mouth tumors in East Africa over 10 years and found many were cancerous, which is important for understanding and treating these diseases.

Methodology

Histopathological reports were retrieved from two major referral hospitals in Tanzania and Uganda over a 10-year period.

Potential Biases

Reliance on general pathologists for oral histopathological diagnosis may introduce bias.

Limitations

The study may not represent the actual prevalence of oral and maxillofacial diseases in the general population due to selective histopathological investigations.

Participant Demographics

53.71% were males and 45.32% were females, with a male to female ratio of 1.2:1.

Digital Object Identifier (DOI)

10.1186/1472-6831-8-19

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