The vertebral body growth plate in scoliosis: a primary disturbance of growth?
2008

Vertebral Body Growth Plates in Scoliosis

Sample size: 29 publication Evidence: moderate

Author Information

Author(s): Gregory Day, Kieran Frawley, Gael Phillips, I Bruce McPhee, Robert Labrom, Geoffrey Askin, Peter Mueller

Primary Institution: University of Queensland

Hypothesis

Do vertebral body growth plates in scoliosis show abnormalities on MR imaging and is there a relationship between MR and histological abnormalities?

Conclusion

The study found MR image abnormalities in scoliotic vertebral body growth plates and a qualitative relationship between MR imaging and histological abnormalities.

Supporting Evidence

  • Four of the 18 MR images showed normal vertebral body growth plates.
  • In 13 scoliotic spines, growth plate deficiencies were observed at or near the apex of the curve.
  • Histological abnormalities were found in four cases with MR imaging abnormalities.

Takeaway

Doctors looked at the growth plates in the spines of kids with scoliosis using special pictures and found some problems that might mean the growth plates aren't working right.

Methodology

The study used high-resolution MR imaging and histological examination of vertebral body growth plates from patients with scoliosis.

Limitations

The study had a small sample size and some MR images were incomplete or of low resolution.

Participant Demographics

The mean age of participants was 10 years, with 11 females and 7 males.

Digital Object Identifier (DOI)

10.1186/1748-7161-3-3

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