Seroprevalence of Human Hantavirus Infection in Ribeirao Preto, Brazil
Author Information
Author(s): Ryan Holmes, Rodrigo Boccanera, Luiz Tadeu M. Figueiredo, Silvia Regina Mancano, Clodoaldo Pane
Primary Institution: University of Texas Medical Branch at Galveston
Hypothesis
What is the prevalence of hantavirus infection in the Ribeirao Preto region?
Conclusion
The seroprevalence of human hantavirus infection in the Ribeirao Preto region was found to be 1.23%.
Supporting Evidence
- The overall antibody prevalence of 1.23% is more than twice that observed in U.S. populations at risk for hantavirus infection.
- Three of the four HPS samples previously confirmed by the ALI in Sao Paulo tested positive by our ELISA.
- Two of the three suspected HPS cases were later confirmed as positive by the ALI.
Takeaway
The study found that a small number of people in Ribeirao Preto have been infected with hantavirus, which can make them very sick.
Methodology
A serologic survey using SNV ELISA was conducted on hospital patients requiring venipuncture.
Limitations
Laboratory confirmation was not available locally, and only presumptive diagnoses could be made until the SNV ELISA was developed.
Participant Demographics
Patients from three regional cities: Ribeirao Preto, Guariba, and Jardinopolis.
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