Management of Skin Cancer with Electrochemotherapy
Author Information
Author(s): Matthiessen Louise Wichmann, Chalmers Richard Ling, Sainsbury David Christopher George, Veeramani Sivakumar, Kessell Gareth, Humphreys Alison Claire, Bond Jane Elisabeth, Muir Tobian, Gehl Julie
Primary Institution: Copenhagen University Hospital Herlev, Denmark
Hypothesis
Electrochemotherapy is an effective palliative treatment for cutaneous metastases.
Conclusion
Electrochemotherapy is an efficient and safe treatment for cutaneous metastases, even in elderly patients.
Supporting Evidence
- Complete response rate was 60% for metastases <3 cm.
- Electrochemotherapy was well-tolerated with no serious adverse events.
- Patients reported high satisfaction with the treatment.
Takeaway
Electrochemotherapy uses electricity to help cancer medicine work better on skin tumors, making it a good option for patients with skin cancer.
Methodology
This phase II study involved patients with cutaneous metastases receiving bleomycin followed by electric pulses to the tumor site.
Limitations
Some patients were lost to follow-up, and the study included a broad spectrum of patients, which may affect the results.
Participant Demographics
Patients were primarily elderly, with a median age of 69.6 years, and included both males and females.
Digital Object Identifier (DOI)
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