A polymorphic tetranucleotide repeat in the CYP19 gene and male breast cancer
2000

CYP19 Gene and Male Breast Cancer

publication

Author Information

Author(s): Young I E, Kurian K M, MacKenzie M A F, Kunkler I H, Cohen B B, Hooper M L, Wyllie A H, Steel C M

Primary Institution: University of Edinburgh

Hypothesis

This study examines the relationship between a tetranucleotide repeat sequence in the CYP19 gene and the development of male breast cancer.

Conclusion

The study found no significant differences between male breast cancer cases and controls.

Supporting Evidence

  • The CYP19 gene codes for the aromatase enzyme involved in oestrogen synthesis.
  • This study is a case-control study examining male breast cancer.

Takeaway

The CYP19 gene is linked to male breast cancer, but this study didn't find any differences between men with and without the disease.

Methodology

This is a case-control study.

Digital Object Identifier (DOI)

10.1054/bjoc.1999.1085

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