Proteome profiling of embryo chick retina
2008
Proteome Profiling of Chick Retina Development
Sample size: 8
publication
Evidence: moderate
Author Information
Author(s): Mizukami Mina, Kanamoto Takashi, Souchelnytskyi Nazariy, Kiuchi Yoshiaki
Primary Institution: Hiroshima University
Hypothesis
The study aims to identify proteins involved in the development of the chick retina.
Conclusion
Thirteen proteins were identified that are differentially expressed in the embryonal retina of chickens at different developmental stages.
Supporting Evidence
- The study identified 13 proteins that change expression during the development of the chick retina.
- Seven proteins were up-regulated and six were down-regulated between embryonic days 7 and 11.
- Some identified proteins are known to regulate cell proliferation and differentiation.
Takeaway
The researchers looked at proteins in chick retinas to see how they change as the chicks develop, finding 13 important proteins.
Methodology
Proteomics-based approach using two-dimensional gel electrophoresis and MALDI mass spectrometry.
Participant Demographics
Embryo chick retinas at days 7, 11, and 15.
Digital Object Identifier (DOI)
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