Treatment of Nevus Depigmentosus with Melanocyte–Keratinocyte Transplantation
Author Information
Author(s): Sanjeev V Mulekar, Ahmed Al Eisa
Primary Institution: National Center for Vitiligo and Psoriasis
Hypothesis
Can a combination of noncultured melanocyte–keratinocyte transplantation and excimer laser effectively treat nevus depigmentosus?
Conclusion
Repigmentation of nevus depigmentosus is possible with grafting techniques, but results are inconsistent and recurrence may occur.
Supporting Evidence
- Three patients showed repigmentation ranging from 80% to 100%.
- Two patients responded poorly to the treatment.
- Quality of repigmentation was unsatisfactory in two of the three responders.
Takeaway
Doctors tried to fix a skin problem called nevus depigmentosus using a special skin treatment, but it didn't always work well.
Methodology
Six patients were treated with a combination of noncultured melanocyte–keratinocyte transplantation and excimer laser, with follow-up ranging from 7 to 30 months.
Limitations
One patient was lost to follow-up, and the quality of repigmentation was unsatisfactory in some cases.
Participant Demographics
1 male and 5 female patients aged 3 to 21 years.
Digital Object Identifier (DOI)
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