Effects of Garcinia kola on Knee Osteoarthritis
Author Information
Author(s): Adegbehingbe Olayinka O, Adesanya Saburi A, Idowu Thomas O, Okimi Oluwakemi C, Oyelami Oyesiku A, Iwalewa Ezekiel O
Primary Institution: Obafemi Awolowo University, Ile-Ife, Nigeria
Hypothesis
Garcinia kola has a positive effect on knee osteoarthritis.
Conclusion
Garcinia kola appeared to have clinically significant analgesic/anti-inflammatory effects in knee osteoarthritis patients.
Supporting Evidence
- Garcinia kola significantly reduced WOMAC pain VAS compared to placebo.
- The onset of pain relief with Garcinia kola was faster than placebo.
- Garcinia kola improved mobility and reduced joint stiffness compared to placebo.
- No significant adverse reactions were reported with Garcinia kola.
Takeaway
Garcinia kola can help reduce pain and improve movement for people with knee problems.
Methodology
A randomized, placebo-controlled, double-blind clinical trial over six weeks with 84 knee osteoarthritis patients.
Limitations
Limited number of knee osteoarthritis patients and lack of research grants for larger studies.
Participant Demographics
58.7% females, mean age 52.5 years.
Statistical Information
P-Value
p < 0.001
Confidence Interval
CI: -2.01 to -1.15
Statistical Significance
p < 0.001
Digital Object Identifier (DOI)
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