Emerging Therapeutics in the Fight Against EV‐D68: A Review of Current Strategies
2024

Emerging Therapeutics in the Fight Against EV-D68

publication Evidence: moderate

Author Information

Author(s): Kalam Nida, Balasubramaniam Vinod R. M. T.

Primary Institution: Jeffrey Cheah School of Medicine and Health Sciences Monash University Malaysia

Hypothesis

The review explores current advancements in antiviral therapies and potential therapeutics to mitigate the impact of EV-D68 infections.

Conclusion

There are currently no FDA-approved antiviral treatments or vaccines for EV-D68, highlighting the urgent need for effective therapeutic strategies.

Supporting Evidence

  • EV-D68 has been linked to outbreaks of acute flaccid myelitis in children.
  • Current antiviral treatments for EV-D68 are lacking, necessitating ongoing research.
  • WIN-like compounds have shown potential but faced issues with resistance and side effects.

Takeaway

EV-D68 is a virus that can make kids very sick, and scientists are trying to find medicines to help fight it because there are no approved treatments yet.

Methodology

This is a review article summarizing various therapeutic strategies and research findings related to EV-D68.

Limitations

The lack of FDA-approved treatments and the rarity of acute flaccid myelitis complicate clinical trials.

Digital Object Identifier (DOI)

10.1111/irv.70064

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