Clinical Versus Pathological Staging in Patients with Resected Ground Glass Pulmonary Lesions
2024

Clinical and Pathological Staging of Ground Glass Pulmonary Lesions

Sample size: 68 publication Evidence: moderate

Author Information

Author(s): Dan Levy Faber, Abed Agbarya, Andrew Lee, Yael Tsenter, Sonia Schneer, Gelis Yulia Robitsky, Ronen Galili

Primary Institution: Carmel Medical Center

Hypothesis

How does the clinical staging of ground glass nodules compare to their pathological staging after surgical resection?

Conclusion

The study found a significant discrepancy between clinical and pathological staging of ground glass nodules, with many lesions being upstaged post-surgery.

Supporting Evidence

  • Over a third of the lesions were upstaged while only a small percentage were downstaged.
  • Ten cases were diagnosed as non-malignant on final pathology.
  • Three cases were diagnosed with a premalignant lesion.

Takeaway

Doctors looked at lung nodules before and after surgery to see if their initial guesses about how serious they were matched the actual findings, and they often didn't.

Methodology

This retrospective study analyzed data from 68 patients who underwent surgery for ground glass nodules, comparing preoperative clinical staging with postoperative pathological staging.

Limitations

The study is retrospective and has a relatively small sample size.

Participant Demographics

The majority of participants were female, with a median age of 70 years.

Digital Object Identifier (DOI)

10.3390/diagnostics14242874

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