Sleep in Wilson’s Disease: A Study
Author Information
Author(s): Archana B. Netto, Sanjib Sinha, Arun B. Panda, Samhita Rao
Primary Institution: National Institute of Mental Health and Neuro Sciences
Hypothesis
The study aimed to detect sleep abnormalities in patients with Wilson's disease using sleep questionnaires.
Conclusion
Sleep disturbances were observed more often in Wilson's disease patients than in controls.
Supporting Evidence
- 15 patients with Wilson's disease had abnormal PSQI scores compared to 6 controls.
- The mean PSQI score was significantly higher in patients than in controls.
- 64% of patients with Wilson's disease had sleep problems, compared to 32% of controls.
Takeaway
People with Wilson's disease have more trouble sleeping compared to healthy people.
Methodology
The study involved 25 patients with Wilson's disease and 24 healthy controls, using the Pittsburgh Sleep Quality Index and Epworth Sleepiness Scale questionnaires.
Limitations
The sample size was small and consisted of a heterogeneous group.
Participant Demographics
25 patients (18 males, 7 females) with a mean age of 24.4 years and 24 male controls with a mean age of 33.1 years.
Statistical Information
P-Value
0.004
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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