Anthracycline-induced toxicity affecting palmar and plantar skin
1989
Skin Changes from Chemotherapy
Sample size: 3
publication
Evidence: low
Author Information
Author(s): A.P. Jones, S.M. Crawford
Primary Institution: Bradford Royal Infirmary and Bradford University
Hypothesis
Frequent administration of anthracycline cytotoxic drugs may cause adverse skin effects.
Conclusion
Anthracycline therapy can lead to painful skin changes on the palms and soles, which improve after stopping treatment.
Supporting Evidence
- Skin changes were observed in three patients receiving anthracycline therapy.
- Symptoms improved after stopping the chemotherapy.
- Previous studies noted similar skin changes with other chemotherapy agents.
Takeaway
Some cancer treatments can hurt your skin on your hands and feet, but it gets better if you stop the medicine.
Methodology
Case reports of three patients experiencing skin toxicity from anthracycline chemotherapy.
Limitations
The study is based on a small number of case reports.
Participant Demographics
Three women aged 66 to 70 with various cancers.
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