Study on Allergy and Helminth Infections in Indonesia
Author Information
Author(s): Hamid Firdaus, Wiria Aprilianto, Wammes Linda J, Kaisar Maria MM, Lell Bertrand, Ariawan Iwan, Uh Hae Won, Wibowo Heri, Djuardi Yenny, Wahyuni Sitti, Schot Robert, Verweij Jaco J, van Ree Ronald, May Linda, Sartono Erliyani, Yazdanbakhsh Maria, Supali Taniawati
Primary Institution: Department of Microbiology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
Hypothesis
How do intestinal helminth infections influence the immune response and allergic disorders in children in Indonesia?
Conclusion
The study aims to determine the relationship between helminth infections and allergic disorders in children.
Supporting Evidence
- Helminth infections are highly prevalent worldwide, affecting populations in low-middle income countries.
- Chronic helminth infections are associated with higher suppressive immune responses.
- Studies suggest a negative association between helminth infections and allergic disorders.
Takeaway
This study is looking at how worms in the belly might affect kids' allergies in Indonesia.
Methodology
A randomized placebo-controlled trial assessing the impact of helminth infections on allergy symptoms and immune responses in school-age children.
Potential Biases
Potential biases may arise from the randomized trial design and participant selection.
Limitations
The study may face challenges in maintaining participant follow-up and controlling for confounding factors.
Participant Demographics
Children aged 5-15 years from semi-urban and rural areas in Flores, Indonesia.
Digital Object Identifier (DOI)
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