Lactobacillus rhamnosus GG as a Probiotic for Giardiasis in Mice
Author Information
Author(s): Nisha Goyal, Ram Prakash Tiwari, Geeta Shukla
Primary Institution: Panjab University
Hypothesis
The study aims to explore the protective potential of various lactobacilli strains for murine giardiasis.
Conclusion
Lactobacillus rhamnosus GG is the most effective probiotic for reducing the duration of giardiasis in mice.
Supporting Evidence
- L. GG was found to be the most effective probiotic in reducing the duration of giardia cycle.
- Mice treated with L. GG became Giardia-free by day 13 post-inoculation.
- Probiotic supplementation reduced cyst excretion compared to Giardia-infected mice.
Takeaway
This study found that a type of good bacteria called Lactobacillus rhamnosus GG can help mice get rid of a nasty bug that makes them sick.
Methodology
BALB/c mice were divided into groups and given different lactobacilli strains before being infected with Giardia lamblia to monitor cyst excretion.
Limitations
The study's findings need to be clinically correlated due to differences in human microflora.
Participant Demographics
BALB/c mice aged 5-6 weeks.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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