Prevalence of chlamydia, gonorrhoea, and trichomoniasis among male and female general populations in sub-Saharan Africa from 2000-2024: A systematic review and meta-regression analysis
2024

STI Prevalence in Sub-Saharan Africa

Sample size: 211 publication Evidence: moderate

Author Information

Author(s): Michalow Julia, Hall Lauren, Rowley Jane, Anderson Rebecca L., Hayre Quinton, Chico R. Matthew, Edun Olanrewaju, Knight Jesse, Kuchukhidze Salome, Majaya Evidence, Reed Domonique M., Stevens Oliver, Walters Magdalene K, Peters Remco PH, Cori Anne, Boily Marie-Claude, Imai-Eaton Jeffrey W.

Primary Institution: Cold Spring Harbor Laboratory

Hypothesis

What is the prevalence of chlamydia, gonorrhoea, and trichomoniasis among male and female populations in sub-Saharan Africa from 2000 to 2024?

Conclusion

Chlamydia prevalence is increasing in sub-Saharan Africa, with significant geographic variation in STI burden.

Supporting Evidence

  • In 2020, chlamydia prevalence was 6.6% among females and 4.7% among males.
  • Gonorrhoea prevalence was 2.4% among females and 1.7% among males.
  • Trichomoniasis prevalence was 6.8% among females and 1.7% among males.
  • Chlamydia prevalence increased by 34.5% from 2010 to 2020 in SSA.

Takeaway

This study looked at how common certain STIs are in Africa and found that chlamydia is becoming more common, especially in some areas.

Methodology

The study used a systematic review and meta-regression analysis of STI prevalence data from various databases.

Potential Biases

Potential biases may arise from the diagnostic test performance adjustments and the selection of included studies.

Limitations

The study is limited by the availability of data and may not represent all regions equally.

Participant Demographics

The study included general populations aged 15-49 from 28 countries in sub-Saharan Africa.

Statistical Information

Confidence Interval

95%CI: 5.0-8.2% for chlamydia among females

Digital Object Identifier (DOI)

10.1101/2024.12.16.24319070

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